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            Why do you have Grey Hair-New health article 10/13/2011
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            Abstract:
            According to new health article Wnt signalling pathway  can cause hair pigmentation.This protein complex already has many proved roles in biological systems which in turn control many biochemical process between stem cells of  melanocytes  and hair follicles.

            This medical research has been presented in NYU Langone Medical Center of New York city.Wnt signalling pathway is a network of proteins.This medical information suggest that manipulation of WNT signalling can be a strategy for targeting pigmentation such as graying hair. This research study also illustrates a model for tissue regeneration. The study provokes the possibility that WNT signalling pathway  is a key for the regulation of melanocyte stem cells and shows how melanocyte behavior is linked with hair regeneration.


            Setting or place:
            This research was lead by Dr. Mayumi lto,assistant professor in the Ronald O. Preleman Department of dermatology at NYU Langone.

            Participants:
            Research team used the Mouse as a models.

            Design:
            Researchers use mouse model to determine  how exactly this protein network( Wnt Signalling) enabled both stem cells of melanocytes and stem cells of hair follicle to act in a same fashion to generate hair colour and growth of hair. Deficiency of Wnt signalling in hair follicle stem cells involves in the stoppage of re-growth of hair but also stop the activation of melanocytes stem cell which is needed to produce colour of hair.The deficiency of this activation in stem cells of melanocyte resulted into de-pigmentation of hair which is gray hair.

            Result:
            It was concluded from this medical information that for regular process of melanocyte stem cells, Wnt signalling is a main regulatory system.and how melanocyte activity is linked with regeneration of hair.This detailed information is a our new understanding about the disease in which melanocyte either destroyed like in hair graying or have abnormal cell growth e.g melanoma.


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